Phytochemical Profiling and Biological Activities of Musa acuminata Peel with Antioxidant and α-Amylase Inhibitory Effects
Keywords:
Musa acuminata, Phytochemicals, DPPH free radical, α-AmylaseAbstract
Peels of Musa acuminata were used as healing medicine in Nepal, especially against gastrointestinal ailments and diabetic patients. However, the scientific evidence towards its use is still lacking. Therefore, the main aim of this research is to bridge the gap between traditional knowledge and scientific inquiry, offering evidence-based insights into the medicinal efficacy of Musa acuminata. The antioxidant activity of ripe peel extract was estimated spectrophotometrically using 2,2-diphenyl-1-picrylhydrazyl radicals (DPPH: 60 µM). Similarly, α-amylase inhibitory activity was analyzed using a modified starch iodine protocol. The percentage yield of the hydroethanolic extract of Musa acuminata ripe peel was found to be 16 %(w/w). Phytochemical analysis revealed the presence of alkaloids, flavonoids, tannins, saponins, terpenoids, steroids, and reducing sugars in the extract, highlighting its diverse chemical composition. The DPPH scavenging activity percentage of ripe peel extract revealed good antioxidant activity with 54.58 土 3.27 %, but showed 5.989土 1.96 % of α-amylase inhibition activity at 0.5 μg/ml concentration of extract, which was very low when compared with voglibose with 97.660 土 98 % at same concentration. The findings suggest that Musa acuminata peels may possess antioxidant and mild amounts of α-amylase inhibition properties. Further exploration of its in-vivo pharmacological studies and clinical trials are needed to confirm their therapeutic potential.
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Published on: 28-01-2025
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Copyright (c) 2025 Suraj Chauhan, Sindhu K.C., Mahashaya Bhandari, Pooja Poudel, Ramkishor Yadav, Prabin Ranabhat, Shila Shrestha, Ansana Shrestha
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