Facile One-Pot Synthesis of Imidazole (MID): A Highly Sensitive Turn-Off Fluorescence Probe for Mercury (II) ion Detection

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Authors

  • Md. Zafer Alam Department of Chemistry, School of Sciences, Maulana Azad National Urdu University, Hyderabad 500032, Telangana, India
  • Salman A. Khan Department of Chemistry, School of Sciences, Maulana Azad National Urdu University, Hyderabad 500032, Telangana, India https://orcid.org/0000-0002-3892-2241
https://doi.org/10.55559/jjbrpac.v3i1.623

Keywords:

Fluorescent sensor, Mercury (II) ion detection, Imidazole, one-pot synthesis, Turn-off Fluorescence, Metal ion sensing

Abstract

A new highly fluorescence and sensitive fluorescent probe 4-(1-(4-methoxyphenyl)-4,5-diphenyl-1H-imidazol-2-yl)-N,N-diphenylaniline (MID) was prepared for the monitoring the mercury (II) ions with fluorometric behaviour in environmental samples. A significant fluorescence quenching was observed with MID in association with Hg2+ ions. MID can detect quiet low concentration of Hg2+ ions. The structure of MID was confirmed by 1H-NMR, 13C-NMR and mass spectrometry. However, the association of and complexation of MID with Hg2+ ions analysed by Job’s plot titration and graph, the results revealed 2:1 ratio of MID with Hg2+ ions. Furthermore, the probe MID respond rapidly, and shows promising candidate for the selective recognition of Hg2+ ions in real samples.

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Published on: 16-03-2026

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How to Cite

Alam , Z., & Khan, S. A. (2026). Facile One-Pot Synthesis of Imidazole (MID): A Highly Sensitive Turn-Off Fluorescence Probe for Mercury (II) ion Detection. Jabirian Journal of Biointerface Research in Pharmaceutics and Applied Chemistry, 3(1), 1–7. https://doi.org/10.55559/jjbrpac.v3i1.623

Issue

Vol. 3 No. 1 (2026): Volume 03 Issue 01

Section

Research Article

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Copyright (c) 2026 Md. Zafer Alam , Salman A. Khan

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