Introduction to extraction and antioxidant activity of alkaloids


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  • Shafat Ahmad Khan Division of Chemistry, Department of Basic Science, School of Basic and Applied Science, Galgotias University, Greater Noida, Uttar Pradesh-201310 India
  • Mahi Chaudhary Division of Chemistry, Department of Basic Science, School of Basic and Applied Science, Galgotias University, Greater Noida, Uttar Pradesh-201310 India


Alkaloids, Radical scavenging, DPPH, FRAP, Antioxidant Activity


Alkaloids are nitrogen-based cyclic compounds. In the recent past, the methods used to extract various types of alkaloids from various sources, and the methods utilised to extract them are all investigated. This review covers the basic synthesis process for alkaloids. Nicotine, cocaine, morphine, quinine, berberine, vinblastine, capsaicin, caffeine, and piperine are some of the alkaloids that have been researched for their biological actions and use. Alkaloids have a wide range of medical applications, making them valuable compounds in this review, the antioxidant activity of alkaloids from various sources found using different methods in the last 7-8 years is presented; however, common assays used to evaluate antioxidant activity are briefly discussed, including DPPH which stands for “2,2–diphenyl-1-picrylhydrazylhydrate free radical scavenger”, Hydroxyl radical scavenging assay and Ferric reducing antioxidant power (FRAP) assay.


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Published on: 2024-01-05

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Khan, S. A., & Chaudhary, M. (2024). Introduction to extraction and antioxidant activity of alkaloids. Jabirian Journal of Biointerface Research in Pharmaceutics and Applied Chemistry, 1(01), 08–17.



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