Ozone effect on morphology erythrocytes and leukocytes in whole blood in vitro

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Authors

  • Martha Rosales Aguilar Microbiology and Biochemistry Department, Facultad de Medicina Psicología de la Universidad Autónoma de Baja California, México
  • Cesar Eduardo Gómez Solís Pain and Ozone and Cell Therapies. Clínica Total Aesthetic, Medicina Regenerativa y Terapia Celular, Tijuana 22666, Baja California, México
  • Manuel Alexander López Ortega Facultad de Medicina y Psicología Universidad Autónoma de Baja California, México https://orcid.org/0009-0001-3880-4712
  • Vanessa Villa Barrera Regenerative Medicine AND Cell Therapy Clínica Total Aesthetic
https://doi.org/10.55559/sjahss.v4i2.464

Keywords:

Ozone effect, erythrocytes, leukocytes, in vitro, morphological changes in blood cells

Abstract

Clinical studies showed gas ozone use is safe; the blood cells can enzymatically control a certain number of antioxidant molecules; in low concentrations, these mechanisms can be triggered, turned on, and stimulated by other leukocyte mechanisms of defense. To observe the effect of ozone on blood erythrocytes and white blood cells when are exposed to therapeutic doses of ozone at concentrations (20, 40, 60, and 90 µL/mL) in volunteer subjects. Blood samples were exposed to concentrations of ozone (20, 40, 60, and 90 µl/mL), evaluated in a hematometer, and blood stains. An alteration in the morphology of leukocyte and erythrocyte cells was observed in blood samples of all concentrations, with statistical significance for neutrophils and monocytes. Ozone in blood in vitro causes a morphological affectation of erythrocytes, monocytes and neutrophils

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References

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Published on: 12-03-2025

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How to Cite

Aguilar, M. R., Solís, C. E. G., Ortega, M. A. L., & Villa Barrera, V. (2025). Ozone effect on morphology erythrocytes and leukocytes in whole blood in vitro. Sprin Journal of Arts, Humanities and Social Sciences, 4(2), 23–29. https://doi.org/10.55559/sjahss.v4i2.464
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