Therapeutic Perspective of Natural Alkaloids in Cervical Cancer Management
Keywords:
Cancer, Woman health Cervical cancer, Health concern, Non-communicable disease, Alkaloids, Natural ProductsAbstract
Cervical cancer is a major global public health concern that requires continuous advancements in screening methodologies and the management of associated challenges. This will make cervical cancer a preventable and treatable condition for women across the world. In this review, we explore the therapeutic potential of natural alkaloids in managing cervical cancer. These compounds are derived from diverse sources such as plants and marine organisms. They demonstrate multifaceted mechanisms, including anti-proliferative, anti-angiogenic, and immunomodulatory effects. Preclinical studies have shown their efficacy on cervical cancer cell lines, while clinical trials have showcased their potential inpatient interventions. To enhance their efficacy, synergistic approaches combining alkaloids with conventional treatments are being considered. Despite challenges such as bioavailability and toxicity, continued research is vital to unlocking the full potential of natural alkaloids. This will offer novel and complementary strategies in cervical cancer therapeutics.
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Published on: 01-01-2024
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